New Technologies & Large Animal Models in Biomedical Research


FMRI of pigExploring new models

Large animal models offer new opportunities to explore important questions in biomedical and dual-purpose research. This symposium will provide a venue to learn about successful research programs that use large animal models, explore ideas and develop collaborations with fellow researchers interested in incorporating these models into their research programs.

programMonday, March 27, 2017
8:00 a.m. to 6:00 p.m.

Heritage Room
University Club of Michigan State University
3535 Forest Road, Lansing, MI 48910

Map and parking information.

Online registration is now closed.

Please contact Kailey Vincent at (517) 432-4449 or email for assistance or questions.

Symposium organized by Dr. Keith Latham, Dr. Asgi Fazleabas and Dr. Almudena Veiga-Lopez on behalf of the Reproductive and Developmental Science Program 

Print-friendly Program (PDF)


8-8:30 Introductory lecture: 
Perspectives of an old cow wonk: Lessons learned from past workshops and the bovine as a dual purpose model in agriculture and biomedicine, James Ireland (Michigan State University)

8:30-8:45 Discussion
Keith Latham, James Pursley and George Smith (Michigan State University)

8:45-9:50 Session 1: Asthma and Respiratory Disease

  • 8:45-8:50 Introduction Keith English (Michigan State University) moderator
  • 8:50-9:20 Alvaro Rojas-Pena, MD (R. Bartlett lab University of Michigan) Animals in artificial organ research
  • 9:20-9:50 Jack Harkema (Michigan State University) Animal models of air pollutant-Induced asthma and rhinitis: What we have learned from monkeys, rats and mice

9:50-10:05 Coffee Break

10:05- 11:25 Session 2: Musculoskeletal Disease in Large Animal Models
Keith Latham (MSU), moderator

  • 10:05-10:10 Keith Latham (MSU),  moderator
  • 10:10-10:40 Clifford Les (Oakland University) Large animal models for bone materials and remodeling research
  • 10:40-11:10 Lisa Larkin (University of Michigan) Using sheep as a large animal model to test ligament/tendon repairs
  • 11:10-11:25 Andrew Shaver (NuGEN) RNA-Seq Solutions

11:25-12:30 Catered light lunch - University Club, Room B106-107 (adjacent to the Heritage Room)

12:30-2:20 Session 3: Environmental Factors Affecting Adult and Fetal Health

Almudena Veiga-Lopez (Michigan State University), moderator

  • 12:30-12:35 Introduction Almudena Veiga-Lopez (Michigan State University)
  • 12:35-1:10 Adam Moeser (Michigan State University) Porcine models of stress-induced gastrointestinal disorders: pathophysiology and translational implications
  • 1:10-1:45 Sean Limesand (University of Arizona) Biomedical animal models for pregnancy
  • 1:45-2:20 RD Roghair (University of Iowa) Translational cardiovascular investigations in sheep and transgenic pigs

2:20-2:30 Coffee Break

2:30-5:00 Session 4: New Technologies
Ariela Shikanov (University of Michigan), moderator

  • 2:45-3:15 Ariela Shikanov (University of Michigan), Engineering the follicle environment
  • 3:15-3:50 Lonnie Shea, (University of Michigan), Local and systemic immunomodulation for regenerative medicine
  • 3:50-4:25 Randy Prather (University of Missouri), Genome editing-state of the art, promises, pitfalls & applications
  • 4:25-5:00 Tom Spencer (University of Missouri), Understanding Fertility in Agriculturally Important Large Animals: Impacts of Technology

5:00-6:00 Reception

Please contact Kailey Vincent at (517) 432-4449 or email with any questions.